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  Wholistic Therapies

Autism Spectrum Disorders & Tourette's Syndrome

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 Definition

Autism, or more correctly, Autistic Spectrum Disorders (ASD), are a series of neurodevelopmental disorders characterised by repetitive behaviours, social withdrawal and communication deficits.

People with ASD display a wide range of cognitive ability, ranging from mental retardation to high functioning adults with an above average IQ. There are three main categories of ASD and two subtypes:

1. Autistic disorder – The diagnosis of autistic disorder is given to individuals with significant impairments in social interaction and communication as well as restricted and repetitive interests, activities and behaviours which are generally evident prior to three years of age.

subtype a. Regressive Autism: When a child appears to develop normally but then starts to lose speech and social skills, typically between the ages of 15 and 30 months.

subtype b. Infantile Autism: When a child does not achieve developmental milestones and is effectively determined to have had autism from infancy.

2. Asperger’s disorder – Individuals with Asperger’s disorder have some difficulties with social
interaction and social communication as well as restricted and repetitive interests, activities
and behaviours. However, those with Asperger’s disorder do not have a significant delay in early language acquisition, cognitive abilities or self-help skills. The condition is often detected later than autism as speech usually develops at the expected age.

3. Pervasive Developmental Disorder – This diagnosis is made when an individual has a marked social impairment but fails to meet the full criteria for either autistic disorder or Asperger’s disorder. These individulas may also have some communication impairments and/or restricted or repetitive interests, activities and behaviours.

The diagnosis of ASD is based exclusively on a particular developmental pattern in the child and has
historically been considered a psychiatric disorder. Whilst a diagnosis is made on observation (see
signs and symptoms below) and there are no quantitative biochemical tests to confirm diagnosis,
there is evidence that indicates numerous biochemical abnormalities in these children, including 
oxidative stress, decreased methylation capacity, mitochondrial dysfunction, heavy metal accumulation, intestinal dysbiosis, inflammatory bowel disease, immune dysregulation and cerebral hypofusion.

 Aetiology / Risk factors

Some possibilities include:

• Heritable genetic polymorphisms influencing detoxification, methylation and dopamine signalling.

• Gender bias, with a 4:1 ratio (males to females)

• Heavy metal exposure – especially mercury, but others may be implicated.

• Immune dysfunction – Severe maternal inflammation, infections, allergy and autoimmunity during 
pregnancy may lead to a ‘cytokine storm’ causing microglial activation and CNS inflammation,
influencing neurodevelopment.

• Immune dysfunction – mild acute or chronic gut mucosal inflammation with ileo-colonic lymphoid
nodular hyperplasia (LNH) leading to “autistic colitis” may be a cause or consequence of systemic
oxidative stress and inflammation associated with autism.

 Signs and Symptoms (Including diagnostic criteria)

Qualitative impairment in social interaction,
as manifested by at least 2 of the following:

• Marked impairment in the use of multiple nonverbal behaviours such as eye-to-eye gaze, facial
expression, body postures, and gestures to regulate social interaction.

• Failure to develop peer relationships appropriate to developmental level

• A lack of spontaneous seeking to share enjoyment, interests, or achievements with other people
(e.g. a lack of showing, bringing, or pointing out objects of interests)

• Lack of social or emotional reciprocity.

Qualitative impairments in communication, as manifested by at least 1 of the following:

• Delay in, or total lack of, development of spoken language (not accompanied by an attempt to
compensate through alternative modes of communication such as gestures or mime).

• In individuals with adequate speech, marked impairment in the ability to initiate or sustain
conversation with others.

• Stereotyped and repetitive use of language or idiosyncratic language.

• Lack of varied, spontaneous make-believe play or social imitative play appropriate to developmental level.

Restricted repetitive and stereotypical patterns of behaviour, interests, and activities, as
manifested by at least one of the following:

• Encompassing preoccupation with one or more stereotyped and restricted patterns of interest that
is abnormal either in intensity or in focus.

• Apparently inflexible adherence to specific, nonfunctional routines or rituals.

• Stereotypical and repetitive motor mannerisms (e.g. hand or finger flapping or twisting, or complex
whole body movements).

• Persistent preoccupation with parts of objects.

Characteristic deviant communication features in autism include a lack of social chat, pragmatic
deficits, pronoun reversal, delayed echolalia, neologisms, lack of emotion in speech, phrase
repetitions, and idiosyncratic use of language. Behavioural manifestations frequently involve
repetitive, self-stimulatory behaviour, especially in more severely affected individuals. This
behaviour can be self-injurious in some, as with arm biting, head slapping, and skin picking.

Diet and Lifestyle
Behavioural modification programs are recommended to assist sufferers and parents establish suitable routines and systems for managing undesirable behaviour.
Programs exist to assist communication development and socialisation.
Depending on the severity, many will need ongoing support and care in adulthood.
Programs are generally more effective when begun early (2-4 years) and are intensive.
Referral to speech therapy and behavioural psychology practitioners is recommended.

Diet
Children should avoid coffee, cola and other caffeinated drinks (if taking stimulants). Diet should be low in sugar and carbohydrates, as hypoglycaemia may trigger symptoms.
Each meal should have protein to provide adequate amino acids for healthy neurotransmitter production.
Emphasise foods high in magnesium, such as green vegetables and nuts.
Children should eat small, regular meals.

EPA and DHA have been shown beneficial for behavioural / learning disorders, so including oily fish in the diet 3-4 times per week will be beneficial.
Avoid known food allergens – an elimination and rechallenge diet may be beneficial to determine sensitivities.
Avoid artificial colours, flavours and preservatives.

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